6-O-Methyldeoxyguanosine

6-O-Methyldeoxyguanosine

• CAS Number: 964-21-6
• UNSPSC Description: O6-Methyldeoxy guanosine; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/6-o-methyldeoxyguanosine.html
• Purity: 99.34
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1C[C@H](N2C=NC3=C2N=C(N)N=C3OC)O[C@@H]1CO
• Molecular Weight: 281.272
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported