(3S,4S)-Tofacitinib

(3S,4S)-Tofacitinib

• CAS Number: 1092578-47-6
• UNSPSC Description: (3S,4S)-Tofacitinib is the less active S-enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/_3S,4S_-Tofacitinib.html
• Purity: 99.75
• Solubility: DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
• Smiles: CN(C1=NC=NC2=C1C=CN2)[C@H]3[C@@H](C)CCN(C(CC#N)=O)C3
• Molecular Weight: 312.37
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported