N-Nitrosodiethylamine-d10

N-Nitrosodiethylamine-d10

• CAS Number: 1219794-54-3
• UNSPSC Description: N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
• Target Antigen: DNA/RNA Synthesis
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Purity: 99.68
• Solubility: 10 mM in DMSO
• Smiles: [2H]C([2H])([2H])C([2H])([2H])N(N=O)C([2H])([2H])C([2H])([2H])[2H]
• Molecular Weight: 112.20
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported