EB-42486
CAT:
804-HY-142647-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
EB-42486
- CAS Number: 2390475-81-5
- UNSPSC Description: EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 < 0.2 nM).
- Target Antigen: LRRK2
- Type: Reference compound
- Related Pathways: Autophagy
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/eb-42486.html
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C(C1=C(C)N(C)C2=NN=NN2C1(C)C)NC3=CC4=C(NN=C4C5=CC=CC=C5)C=C3
- Molecular Weight: 414.46
- References & Citations: [1]Garofalo AW, et al. Selective Inhibitors of G2019S-LRRK2 Kinase Activity. J Med Chem. 2020 Dec 10;63(23):14821-14839.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported