Login

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

CAT:
804-HY-136658-04
Size:
25 mg
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea - image 1

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

  • CAS Number: 1313019-65-6
  • UNSPSC Description: STAT3-IN-7 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects[1].
  • Target Antigen: Apoptosis; STAT
  • Type: Reference compound
  • Related Pathways: Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/stat3-in-7.html
  • Smiles: O=C(NC1=CC=C(OC2=CC=C(C#N)C=C2)C=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3
  • Molecular Weight: 431.80
  • References & Citations: [1]Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15(4):R63.
  • Shipping Conditions: Room Temperature