Diphenhydramine-d6 (hydrochloride)
CAT:
804-HY-B0303AS-01
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Diphenhydramine-d6 (hydrochloride)
- CAS Number: 1189986-72-8
- UNSPSC Description: Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].
- Target Antigen: Endogenous Metabolite; Histamine Receptor; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling;Others
- Field of Research: Inflammation/Immunology; Endocrinology
- Purity: 98.83
- Solubility: 10 mM in DMSO
- Smiles: [2H]C([2H])([2H])N(C([2H])([2H])[2H])CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
- Molecular Weight: 297.85
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Simons FE. H1-receptor antagonists. Comparative tolerability and safety. Drug Saf. 1994;10(5):350-380.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported