Numb (phospho-Ser276) rabbit pAb
CAT:
855-ES14425-02
Size:
100 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Numb (phospho-Ser276) rabbit pAb
- Description: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
- Synonyms: Protein numb homolog (h-Numb) (Protein S171)
- Gene ID: 8650
- UniProt: P49757
- Cellular Locus: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side. Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side. Localizes to perinuclear endosomes in an AAK1-dependent manner..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthesized phosho peptide around human Numb (Ser276)
- Clonality: Polyclonal
- Validated Applications: WB
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:1000-2000
- Molecular Weight: 70kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.