ErSO-DFP
CAT:
804-HY-144070-03
Size:
25 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ErSO-DFP
- CAS Number: 2768139-76-8
- UNSPSC Description: ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator. ErSO-DFP has enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells with a wider selectivity window than ErSO.ErSO-DFP displays antitumor activity and leads to profound regression of MCF-7 tumors in mice model[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/erso-dfp.html
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C1NC2=C(C=CC=C2[C@]1(N3CCC(F)(CC3)F)C4=CC=C(C=C4)O)C(F)(F)F
- Molecular Weight: 412.35
- References & Citations: [1]Matthew W Boudreau, et al. Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer. J Med Chem. 2022 Mar 10;65(5):3894-3912.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported