6-CEPN
CAT:
804-HY-114569-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
6-CEPN
- CAS Number: 1054549-73-3
- UNSPSC Description: 6-CEPN is a RAS inhibitor. 6-CEPN can inhibit RAS activation by binding to Icmt binding sites. 6-CEPN has anticancer activity. 6-CEPN can block cancer cells in the G1 phase. 6-CEPN can induce autophagy and necrosis of Cancer cells (Icmt: isovalerylcysteine carboxymethyltransferase)[1].
- Target Antigen: Autophagy; Cyclin G-associated Kinase (GAK); Ras
- Type: Reference compound
- Related Pathways: Autophagy;Cell Cycle/DNA Damage;GPCR/G Protein;MAPK/ERK Pathway
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/6-cepn.html
- Purity: 99.17
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C1CC(OC2=C1C(O)=C(C(O)=C2)/C=C/C3=CC=CC=C3)C4=CC=C(C=C4)O
- Molecular Weight: 374.39
- References & Citations: [1]Zhao Y, et al. 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells[J].European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR), 2016, 68(Null).
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported