Carvedilol Glucuronide

CAT:

804-HY-137387

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CAS Number: 114869-83-9
UNSPSC Description: Carvedilol Glucuronide is the metabolite of Carvedilol (HY-B0006). Carvedilol (BM 14190) is an antagonist for β/α-1 adrenergic receptor. Carvedilol inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol is an antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[1].
Target Antigen: Drug Metabolite
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Applications: Neuroscience-Neuromodulation
Field of Research: Others; Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/carvedilol-glucuronide.html
Smiles: OC([C@@H](O[C@H]1OC(COC2=C3C4=CC=CC=C4NC3=CC=C2)CNCCOC5=C(OC)C=CC=C5)[C@@H](O)[C@H](O)[C@H]1O)=O
Molecular Weight: 582.60
References & Citations: [1]Hanioka N, et al., Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes. Pharmacology. 2012;90(3-4):117-24.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-137387	Carvedilol Glucuronide
HY-B0006-02	Carvedilol
HY-B0006-03	Carvedilol
HY-B0006-01	Carvedilol
HY-12767	Carvedilol metabolite 4-Hydroxyphenyl Carvedilol
HY-12767S1	Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-d4
HY-B0006S1	Carvedilol-d4
HY-B0006B-02	(S)-Carvedilol
HY-B0006B-01	(S)-Carvedilol
HY-B0006C-05	(R)-Carvedilol

Cat	Name
T35845-5mg	(R,S)-Carvedilol Glucuronide
MBS5797115	(R,S)-Carvedilol Glucuronide
T35845-10mg	(R,S)-Carvedilol Glucuronide
T35845-1g	(R,S)-Carvedilol Glucuronide
T35845-1mg	(R,S)-Carvedilol Glucuronide
T35845-50mg	(R,S)-Carvedilol Glucuronide
TRC-C184615-5MG	Carvedilol N-beta-D-Glucuronide
sc-504704	Carvedilol N-β-D-Glucuronide
TRC-C184620-100MG	Carvedilol N’-beta-D-Glucuronide
sc-500277	O-Desmethyl carvedilol β-D-glucuronide