CD38 inhibitor 3
CAT:
804-HY-156120-04
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD38 inhibitor 3
- CAS Number: 2857868-82-5
- UNSPSC Description: CD38 inhibitor 3 (compound 1) is a potent CD38 inhibitor (IC50=11 nM). CD38 inhibitor 3 can promote mitochondrial biogenesis, reduce lactate levels, and increase NAD+ content and Nrf2 expression. In a model of mitochondrial myopathy, CD38 inhibitor 3 increases muscle contraction/development and improves exercise tolerance in Pus1-/- mice[1].
- Target Antigen: CD38
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/cd38-inhibitor-3.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(C1=NC(N2C=NC=C2)=NC(C(F)(F)F)=C1)NC3=CN=C(OCCOC)N=C3
- Molecular Weight: 409.32
- References & Citations: [1]Li Y, et al. Discovery of a First-in-Class CD38 Inhibitor for the Treatment of Mitochondrial Myopathy. J Med Chem. 2023 Sep 11.. .
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported