ZW4864 (free base)
CAT:
804-HY-132300A-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZW4864 (free base)
- CAS Number: 2632259-92-6
- UNSPSC Description: ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein?protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM[1].
- Target Antigen: β-catenin
- Type: Reference compound
- Related Pathways: Stem Cell/Wnt
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/zw4864-free-base.html
- Purity: 99.42
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C([C@H]1CN(C2=CC=CC(OC(C)(C)C(N3CCNCC3)=O)=C2)CCC1)N(C4CC4)CC5=CC=C(C6=CNN=C6)C=C5
- Molecular Weight: 570.72
- References & Citations: [1]Wang Z, et al. Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction. J Med Chem. 2021;64(16):12109-12131.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported