CaMK2 (Phospho-Thr286) Rabbit pAb
CAT:
855-ES17871-02
Size:
100 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CaMK2 (Phospho-Thr286) Rabbit pAb
- Description: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
- Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta;CaMK-II subunit delta;EC 2.7.11.17)
- Gene ID: 817
- UniProt: Q9UQM7/Q13557
- Cellular Locus: Cell junction, synapse. Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Postsynaptic lipid rafts..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000, ELISA (peptide)1:5000-20000
- Molecular Weight: 54kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.