Oleanolic acid
CAT:
804-HY-N0156-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Oleanolic acid
- CAS Number: 508-02-1
- UNSPSC Description: Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
- Target Antigen: Autophagy; Endogenous Metabolite; HIV; MAP3K
- Type: Natural Products
- Related Pathways: Anti-infection;Autophagy;MAPK/ERK Pathway;Metabolic Enzyme/Protease
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Oleanolic-Acid.html
- Purity: 98.0
- Solubility: DMF : 45.45 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : 5 mg/mL (ultrasonic)
- Smiles: C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C
- Molecular Weight: 456.70
- References & Citations: [1]Zhao X, et al. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015 Feb;400(1-2):1-7.|[2]Liu J, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014 Nov;25(11):1154-60.|[3]Liu J, et al. p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid. Asian Pac J Cancer Prev. 2014;15(11):4519-25.|[4]Martín R, et al. Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the human disease. J Mol Cell Cardiol. 2014 Jul;72:250-62.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Launched