Hydrocortisone cypionate

Hydrocortisone cypionate

• CAS Number: 508-99-6
• UNSPSC Description: Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
• Target Antigen: Glucocorticoid Receptor
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Endocrinology
• Assay Protocol: https://www.medchemexpress.com/Hydrocortisone_cypionate.html
• Purity: 98.04
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: C[C@@]1([C@@]2(O)C(COC(CCC3CCCC3)=O)=O)[C@](CC2)([H])[C@@](CCC4=CC5=O)([H])[C@]([C@]4(CC5)C)([H])[C@@H](O)C1
• Molecular Weight: 486.64
• References & Citations: [1]F?rster C, et al. Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. J Physiol. 2008 Apr 1;586(7):1937-49.|[2]Bellinghausen I, et al. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J Allergy Clin Immunol. 2001 Aug;108(2):242-9.|[3]Chappell D, et al. Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx. Anesthesiology. 2007 Nov;107(5):776-84.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched