4-Hydroxyphenyl acetate

4-Hydroxyphenyl acetate

• CAS Number: 3233-32-7
• UNSPSC Description: 4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/4-hydroxyphenyl-acetate.html
• Purity: 99.98
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C)OC(C=C1)=CC=C1O
• Molecular Weight: 152.149
• References & Citations: [1]Hanus J, et, al. 4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5048-59.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported