Anti-Blood Group ABH PE

Anti-Blood Group ABH PE

• Specifications: The mouse monoclonal antibody HE-10 agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients of blood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.
• CAS Number: 9007-83-4
• Certification: RUO
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
• Target Antigen: Blood Group ABH
• Isotype: IgM
• Clone: HE-10
• Applications: Flow cytometry: Recommended dilution: 2-5 μg/mL.
• Validated Applications: FC
• Concentration: 0.1 mg/mL
• Format: PE
• Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
• References & Citations: *Nemec M, Drimalova D, Horejsi V, Vanak J, Bartek J, Viklicky V: Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang. 198752(1-2):125-8., URL: https://www.ncbi.nlm.nih.gov/pubmed/2440181?dopt=A,*Vanak J, Drimalova D, Smyslova O, Nemec M, Viklicky V, Wisniewski K: Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma. 198936(4):479-88. , URL: https://www.ncbi.nlm.nih.gov/pubmed/2475797?dopt=A,
• Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.