Brimonidine

CAT:

804-HY-B0659-06

Size:

100 mg

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CAS Number: 59803-98-4
UNSPSC Description: Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist.
Target Antigen: Adrenergic Receptor
Type: Reference compound
Related Pathways: GPCR/G Protein;Neuronal Signaling
Field of Research: Endocrinology; Cancer; Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/uk-14,304.html
Purity: 99.99
Solubility: DMSO : 50 mg/mL (ultrasonic)
Smiles: BrC1=C2N=CC=NC2=CC=C1NC3=NCCN3
Molecular Weight: 292.13
References & Citations: [1]Andorn, A.C., M.A. Carlson, and R.C. Gilkeson, Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity states with alpha 2-adrenergic selectivity and differing affinities for GTP. Life Sci, 1988. 43(22): p. 1805-12.|[2]Cambridge, D., UK-14,304, a potent and selective alpha2-agonist for the characterisation of alpha-adrenoceptor subtypes. Eur J Pharmacol, 1981. 72(4): p. 413-5.|[3]Chopin, P., F.C. Colpaert, and M. Marien, Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther, 1999. 288(2): p. 798-804.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: Launched