Esomeprazole

Esomeprazole

• CAS Number: 119141-88-7
• UNSPSC Description: Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].
• Target Antigen: Bacterial; Proton Pump
• Type: Reference compound
• Related Pathways: Anti-infection;Membrane Transporter/Ion Channel
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/esomeprazole.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=[S@](C1=NC2=CC=C(OC)C=C2N1)CC3=NC=C(C)C(OC)=C3C
• Molecular Weight: 345.424
• References & Citations: [1]Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46.|[2]Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16.|[3]Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.
• Shipping Conditions: Room Temperature
• Clinical Information: Launched