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Aminooxy-PEG1-azide

CAT:
804-HY-126948-02
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Aminooxy-PEG1-azide - image 1

Aminooxy-PEG1-azide

  • CAS Number: 2100306-70-3
  • UNSPSC Description: Aminooxy-PEG1-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminooxy-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • Target Antigen: PROTAC Linkers
  • Type: Reference compound
  • Related Pathways: PROTAC
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/aminooxy-peg1-azide.html
  • Solubility: 10 mM in DMSO
  • Smiles: NOCCOCCN=[N+]=[N-]
  • Molecular Weight: 146.15
  • References & Citations: [1] Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported