1,3,5-Tri-O-benzoyl-a-D-ribofuranose

1,3,5-Tri-O-benzoyl-a-D-ribofuranose

• CAS Number: 22224-41-5
• UNSPSC Description: 1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1-3-5-tri-o-benzoyl-a-d-ribofuranose.html
• Purity: 99.75
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC=CC=C1)OC[C@H]2O[C@H](OC(C3=CC=CC=C3)=O)[C@H](O)[C@@H]2OC(C4=CC=CC=C4)=O
• Molecular Weight: 462.45
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported