Anti-Myc (phospho-Thr58) Antibody
CAT:
14-43034-1
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Myc (phospho-Thr58) Antibody
- Description: Rabbit Polyclonal Antibody specific to Myc (phospho-Thr58)
- Product Name Alternative: Anti-Myc (phospho-Thr58) Rabbit Polyclonal Antibody
- CAS Number: 9007-83-4
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: Peptide sequence that includes phosphorylation site of threonine 58 (L-P-T(p)-P-P) derived from human Myc and conjugated to KLH.
- Target: Myc (phospho-Thr58)
- Clonality: Polyclonal
- Type: Antibody
- Applications: WB, IHC
- Field of Research: Phosphospecific Antibodies
- Purification Method: Affinity-purified on phosphopeptide; non-phosphopeptidereactive antibodies were removed by chromatography on non-phosphorylated peptide
- Concentration: 1.0 mg/mL
- Dilution: Dilute in PBS or medium that is identical to that used in the assay system.
- Format: Purified
- Form: Liquid
- Buffer: Phosphate Buffered Saline
- Additionnal Information: Immunoblotting: use at dilution of 1:500-1:1,000. A band of ~60kDa is detected.
Immunohistochemistry: use at dilution of 1:50- 1:100.
These are recommended working dilutions.
End user should determine optimal dilutions for their applications. - Storage Conditions: This antibody is stable for at least one (1) year at -20°C.
- Specificity: This antibody detects endogenous human, mouse, and rat Myc only when phosphorylated at threonine 58.
- Formulation: PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Buffer pH: pH 7.4
- Target Background: Myc (c-Myc) is a regulator gene that codes for transcription factor Myc. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. A mutated version of Myc is found in many cancers which causes Myc to be constitutively expressed.