Complement factor D-IN-1
CAT:
804-HY-102034-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Complement factor D-IN-1
- CAS Number: 1386455-76-0
- UNSPSC Description: Complement factor D-IN-1 is a potent and selective small-molecule reversible factor d inhibitor, with IC50s of 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively.
- Target Antigen: Complement System
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/small-molecule_reversible_Factor_D-IN-1.html
- Purity: 98.85
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(N)C1=NN(CC(N2[C@H](C(NC3=CC=CC(Br)=N3)=O)C[C@@H]4[C@H]2C4)=O)C5=C1C=CC=C5
- Molecular Weight: 483.32
- References & Citations: [1]Lorthiois E, et al. Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D InhibitorsDemonstrating Alternative Complement Pathway Inhibition in Vivo. J Med Chem. 2017 Jul 13;60(13):5717-5735.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported