Indican
CAT:
804-HY-122009-03
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Indican
- Product Name Alternative: Indoxyl-β-D-glucoside
- CAS Number: 487-60-5
- UNSPSC Description: Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2].
- Target Antigen: Fluorescent Dye; OAT
- Type: Dye Reagents
- Related Pathways: Membrane Transporter/Ion Channel;Others
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/indican.html
- Purity: 99.88
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)|Methanol : 83.33 mg/mL (ultrasonic)
- Smiles: O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)OC2=CNC3=C2C=CC=C3)CO
- Molecular Weight: 295.291
- References & Citations: [1]Shiuan-Pey Lin, et al. Transporter-mediated interaction of indican and methotrexate in rats. J Food Drug Anal. 2018 Apr;26(2S):S133-S140.|[2]Yu-Chi Hou, et al. Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-beta-D-glucoside (indican) in rats. Toxicon. 2008 Sep 1;52(3):440-4.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported