N,N-Dimethylacetamide (Standard)

N,N-Dimethylacetamide (Standard)

• CAS Number: 127-19-5
• UNSPSC Description: N,N-Dimethylacetamide (Standard) is the analytical standard of N,N-Dimethylacetamide. This product is intended for research and analytical applications. N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease[1][2][3].
• Target Antigen: NF-κB
• Type: Reference Standards
• Related Pathways: NF-κB
• Field of Research: Metabolic Disease; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/n-n-dimethylacetamide-standard.html
• Smiles: CC(N(C)C)=O
• Molecular Weight: 87.12
• References & Citations: [1]Sundaram S, et al. N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth. Am J Pathol. 2013 Aug;183(2):422-30.|[2]Wei ZH, et al. N,N-dimethylacetamide targets neuroinflammation in Alzheimer's disease in in-vitro and ex-vivo models. Sci Rep. 2023 May 1;13(1):7077.|[3]Koya JB, et al. FDA-Approved Excipient N, N-Dimethylacetamide Attenuates Inflammatory Bowel Disease in In Vitro and In Vivo Models. Fortune J Health Sci. 2022;5:499-509.
• Shipping Conditions: Room temperature