HSD17B13-IN-53
CAT:
804-HY-163252
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HSD17B13-IN-53
- CAS Number: 2770246-81-4
- UNSPSC Description: HSD17B13-IN-53 (Compound 88) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-53 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
- Target Antigen: 17β-HSD
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/hsd17b13-in-53.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=C(C)C(N=CN3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O
- Molecular Weight: 538.30
- References & Citations: [1]Anandan, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-09-07.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported