Ginkgolic acid C17:1 (Standard)

Ginkgolic acid C17:1 (Standard)

• CAS Number: 111047-30-4
• UNSPSC Description: Ginkgolic acid C17:1 (Standard) is the analytical standard of Ginkgolic acid C17:1. This product is intended for research and analytical applications. Ginkgolic acid C17:1 is a fatty acid synthase (FAS) inhibitor with an IC50 of 10.5 µM. Ginkgolic acid C17:1 shows anti-tumor activity by inhibiting the phosphorylation of STAT3 and inducing apoptosis. Ginkgolic acid C17:1 can block the interaction between S-RBD and ACE2, and has anti-SARS-CoV-2-S pseudovirus activity. Ginkgolic acid C17:1 inhibits the biofilm formation of enterohemorrhagic Escherichia coli and Staphylococcus aureus[1].
• Target Antigen: Apoptosis; Fatty Acid Synthase (FASN); PTEN; SARS-CoV; STAT
• Type: Reference Standards
• Related Pathways: Anti-infection;Apoptosis;JAK/STAT Signaling;Metabolic Enzyme/Protease;PI3K/Akt/mTOR;Stem Cell/Wnt
• Field of Research: Cancer; Infection
• Assay Protocol: https://www.medchemexpress.com/ginkgolic-acid-c17-1-standard.html
• Smiles: O=C(O)C1=C(O)C=CC=C1CCCCCCCCC/C=C\CCCCCC
• Molecular Weight: 374.56
• References & Citations: [1]Baek SH, et al. Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase. Molecules. 2017 Feb 13;22(2). pii: E276.
• Shipping Conditions: Room temperature