WEHI-9625
CAT:
804-HY-128777-01
Size:
1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
WEHI-9625
- CAS Number: 2595314-46-6
- UNSPSC Description: WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX[1].
- Target Antigen: Apoptosis; VDAC
- Type: Reference compound
- Related Pathways: Apoptosis;Membrane Transporter/Ion Channel
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/wehi-9625.html
- Purity: 99.46
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C(S1)=CC(CS2(=O)=O)=C1C3=C2C=C(C4=CC=CC=C4C(C5=CC=C(OC)C=C5)=O)C=C3)NCC6=CC=C(C)C=C6
- Molecular Weight: 593.71
- References & Citations: [1]van Delft MF, et al. A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis. Nat Chem Biol. 2019 Oct 7.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported