Human SLC1A2 Protein, Flag,His Tag (Detergent)

Human SLC1A2 Protein, Flag,His Tag (Detergent)

• Background: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]
• Description: Human SLC1A2 Protein, Flag,His Tag (SL2-H52D6) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Lys 574 (Accession # P43004).
• Specifications: This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 66.0 kDa. The protein migrates as 55-70 KDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Ala 2 - Lys 574
• Host: HEK 293
• Target: SLC1A2
• Conjugation: Unconjugated
• Tag: N-Flag & C-10×His
• Source: Human
• Stability: The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
• Endotoxin: 1.0 EU per μg
• Purity: 90%
• Bioactivity: Immobilized Human SLC1A2 Protein, Flag,His Tag (Cat. No. SL2-H52D6) at 10 μg/mL (100 μL/well) can bind Monoclonal Anti-Human SLC1A2 antibody, Mouse IgG with a linear range of 0.156-1.25 μg/mL (QC tested).
• Format: Liquid
• Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Additives: Glycerol
• Molecular Weight: 66.0 kDa
• Shipping Conditions: Dry ice
• Storage Conditions: -70°C