Tazobactam

Tazobactam

• CAS Number: 89786-04-9
• UNSPSC Description: Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research[1][2].
• Target Antigen: Antibiotic; Bacterial; Beta-lactamase
• Type: Natural Products
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Cancer
• Assay Protocol: https://www.medchemexpress.com/Tazobactam.html
• Purity: 99.94
• Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
• Smiles: O=C([C@@H]([C@@](CN1N=NC=C1)(C)S([C@]2([H])C3)(=O)=O)N2C3=O)O
• Molecular Weight: 300.29
• References & Citations: [1]Harada Y, et, al. In vitro and in vivo activities of piperacillin-tazobactam and meropenem at different inoculum sizes of ESBL-producing Klebsiella pneumoniae. Clin Microbiol Infect. 2014 Nov;20(11):O831-9.|[2]Higashitani F, et, al. Inhibition of beta-lactamases by tazobactam and in-vitro antibacterial activity of tazobactam combined with piperacillin. J Antimicrob Chemother. 1990 Apr;25(4):567-74.Antimicrob Agents Chemother. 2023 May 18;e0160322.|bioRxiv. 2024 May 10.|Eur J Clin Microbiol Infect Dis. 2024 Nov 26.|Int J Med Microbiol. 2021 Oct;70(10).|Microbiol Spectr. 2022 Dec 8;e0303822.|Microbiol Spectr. 2023 Apr 24;e0069223.|Research Square Preprint. 2021 Aug.|Antimicrob Agents Chemother. 2024 Oct 4:e0077524.|Nat Commun. 2022 Mar 2;13(1):1116.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched