NNC 38-1049

NNC 38-1049

• CAS Number: 757183-18-9
• UNSPSC Description: NNC 38-1049 is an orally active, potent and competitive histamine H3 receptor antagonist. NNC 38-1049 produced an increase in extracellular levels of histamine in the paraventricular nucleus. NNC 38-1049 decreases food intake and body weight, which is promising for research of obesity[1].
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/nnc-38-1049.html
• Purity: 99.84
• Solubility: DMSO : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=CC=C(Cl)C=C1)CCC(N2CCN(C3CCCC3)CC2)=O
• Molecular Weight: 348.87
• References & Citations: [1]Malmlöf K, et al. Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight. Int J Obes (Lond). 2005 Dec;29(12):1402-12.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported