Boc-piperazine-benzoic acid

Boc-piperazine-benzoic acid

• CAS Number: 162046-66-4
• UNSPSC Description: Boc-piperazine-benzoic acid is a PROTAC linker and can be used in the synthesis of PROTACs, such as PROTAC androgen receptor (AR) degrader ARD-2128 (HY-13229)[1].
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/boc-piperazine-benzoic-acid.html
• Purity: 99.37
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)C1=CC=C(N2CCN(C(OC(C)(C)C)=O)CC2)C=C1
• Molecular Weight: 306.362
• References & Citations: [1]Han X, et al. Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer. J Med Chem. 2021;64(17):12831-12854.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported