Pomalidomide-C7-NH2

Pomalidomide-C7-NH2

• CAS Number: 2093387-55-2
• UNSPSC Description: Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) (Compound 24g) is an E3 Ligase Ligand-Linker Conjugates consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-C7-NH2 can be used for synthesis of PROTACs[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-c7-nh2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCCCCCCN)=CC=C3)=O)=O
• Molecular Weight: 386.44
• References & Citations: [1]Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported