OB-24

OB-24

• CAS Number: 939825-12-4
• UNSPSC Description: OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA)[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ob-24.html
• Purity: 98.03
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
• Smiles: BrC1=CC=C(CCC2(CN3C=CN=C3)OCCO2)C=C1.Cl
• Molecular Weight: 373.67
• References & Citations: [1]Alaoui-Jamali MA, et al. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009;69(20):8017-8024.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported