Trospium (chloride)
CAT:
804-HY-B0461-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Trospium (chloride)
- CAS Number: 10405-02-4
- UNSPSC Description: Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2].
- Target Antigen: mAChR
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease; Cancer
- Assay Protocol: https://www.medchemexpress.com/Trospium-chloride.html
- Purity: 99.88
- Solubility: DMSO : 25 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
- Smiles: [H][C@@]12CC[C@@](C[C@@H](OC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=O)C2)([H])[N+]15CCCC5.[Cl-]
- Molecular Weight: 427.96
- References & Citations: [1]David RP Guay. Trospium chloride: an update on a quaternary anticholinergic for treatment of urge urinary incontinence. Ther Clin Risk Manag. 2005 Jun; 1(2): 157–167.|[2]Eric S Rovner, et al. Trospium chloride in the management of overactive bladder. Drugs. 2004;64(21):2433-46.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched