Prednisone acetate

Prednisone acetate

• CAS Number: 125-10-0
• UNSPSC Description: Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].
• Target Antigen: Glucocorticoid Receptor; Interleukin Related; Notch
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Neuronal Signaling;Stem Cell/Wnt;Vitamin D Related/Nuclear Receptor
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/prednisone-acetate.html
• Purity: 99.92
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: C[C@@]1(C2)[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O
• Molecular Weight: 400.46
• References & Citations: [1]Prednisolone acetate|[2]Wang Y, et al. Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation [J]. Brain Research, 2023, 1805: 148270.|[3]Zhou M, Qu R, Yin X, et al. Prednisone acetate modulates Th1/Th2 and Th17/Treg cell homeostasis in experimental autoimmune uveitis via orchestrating the Notch signaling pathway [J]. International Immunopharmacology, 2023, 116: 109809.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched