HA-CD44 interaction inhibitor 1
CAT:
804-HY-149898-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HA-CD44 interaction inhibitor 1
- CAS Number: 3052354-70-5
- UNSPSC Description: Antitumor agent-109 (compound 6) is an inhibitor of hyaluronic acid (HY-B0633A) targeting to CD44, as well as an anti-tumor agent. Hyaluronic acid interacts with differentiation cluster 44 (CD44) and is involved in tumor growth and invasion. Antitumor agent-109 inhibits MDA-MB-231 cells with EC50 value of 0.59 μM[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ha-cd44-interaction-inhibitor-1.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
- Smiles: COC1=C(OC)C(OC)=CC(CN2CC3=C(C(Br)=CC=C3)CC2)=C1
- Molecular Weight: 392.29
- References & Citations: [1]Espejo-Román JM, et al. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Eur J Med Chem. 2023 Oct 5;258:115570.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported