17-HDHA

17-HDHA

• CAS Number: 90780-52-2
• UNSPSC Description: 17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells[1][2].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/17-hdha.html
• Solubility: 10 mM in DMSO
• Smiles: CC/C=C\CC(O)/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
• Molecular Weight: 344.49
• References & Citations: [1]Ramon S, et al. The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant? J Immunol. 2014 Dec 15;193(12):6031-40.|[2]Ramon S, et al. Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells. J Immunol. 2012 Jul 15;189(2):1036-42.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported