25(R,S)-Ruscogenin

25(R,S)-Ruscogenin

• CAS Number: 874485-32-2
• UNSPSC Description: Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway[1]. And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su
• Target Antigen: Akt; Apoptosis; mTOR; PI3K
• Type: Natural Products
• Related Pathways: Apoptosis;PI3K/Akt/mTOR
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/25-r-s-ruscogenin.html
• Purity: 99.83
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C[C@@]12[C@]3([H])[C@@](C[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](C[C@H]5O)O)=CC4)C)([H])CC2)([H])O[C@]6(CCC(CO6)C)[C@H]3C
• Molecular Weight: 430.62
• References & Citations: [1]Hua H, Zhu Y, Song YH. Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathway. Biomed Pharmacother. 2018;101:115-122.|[2]Wu Y, Wang Y, Gong S, et al. Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling. Biomed Pharmacother. 2020;125:109868.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported