Metolazone-d7

Metolazone-d7

• CAS Number: 2714484-71-4
• UNSPSC Description: Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.
• Target Antigen: Thrombin
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Purity: 99.90
• Solubility: 10 mM in DMSO
• Smiles: O=S(C1=CC2=C(NC(C)N(C3=C([2H])C([2H])=C([2H])C([2H])=C3C([2H])([2H])[2H])C2=O)C=C1Cl)(N)=O
• Molecular Weight: 372.88
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Stern A. Metolazone, a diuretic agent. Am Heart J. 1976 Feb;91(2):262-3.|[3]Thompson DM. A new antihypertensive: metolazone treatment of hypertension. J Kans Med Soc. 1977 Jul;78(7):337-9, 342.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported