Arginase inhibitor 1

Arginase inhibitor 1

• CAS Number: 1345808-25-4
• UNSPSC Description: Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively.
• Target Antigen: Arginase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Arginase-inhibitor-1.html
• Solubility: DMSO : ≥ 48 mg/mL|H2O : ≥ 30 mg/mL
• Smiles: O=C(O)[C@@](CCN1CCCCC1)(N)CCCCB(O)O
• Molecular Weight: 286.18
• References & Citations: [1]Van Zandt MC, et al. Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potentinhibitors of human arginases I and II for treatment of myocardial reperfusion injury. J Med Chem. 2013 Mar 28;56(6):2568-80.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported