(S,R,S)-AHPC-Me-C5-COOH
CAT:
804-HY-130849-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(S,R,S)-AHPC-Me-C5-COOH
- CAS Number: 2229976-21-8
- UNSPSC Description: (S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-me-c5-cooh.html
- Purity: 96.87
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(N[C@H](C1=CC=C(C2=C(C)N=CS2)C=C1)C)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCC(O)=O)=O)=O)C[C@H](O)C3
- Molecular Weight: 586.74
- References & Citations: [1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported