Mouse Anti-Chicken CD1.1
CAT:
544-MBS673986-01
Size:
0.5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mouse Anti-Chicken CD1.1
- CAS Number: 9007-83-4
- Reactivity: Chicken
- Storage Conditions: The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C.
- Specificity: Chicken CD1.1
CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells1. Chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution2. Two proteins have been identified: CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells (B cells and some macrophages) and CD8a+ cells (some T and NK cells). CD1.2 is expressed in TCR1 + cells (gamma delta cells) but is nearly undetectable in TCR2+ and TCR3+ cells (alpha and Beta T cells)1. Clone CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells1. - Short Name: [CD1.1]