TCMCB07 (TFA)
CAT:
804-HY-P5971A-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TCMCB07 (TFA)
- UNSPSC Description: TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia[1].
- Target Antigen: Melanocortin Receptor
- Type: Peptides
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/tcmcb07-tfa.html
- Purity: 99.69
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: N/C(N)=N/CCC[C@@H](C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@H](C(NC(C(N3[C@@H](C(N)=O)CCC3)=O)C(C)C)=O)CCCCNC(C[C@@H]4NC([C@H](CCCC)NC(C)=O)=O)=O)=O)=O)NC([C@@H](CC5=CC=C(C=CC=C6)C6=C5)NC([C@H](CCC7)N7C4=O)=O)=O.OC(C(F)(F)F)=O.[x]
- Molecular Weight: 1230.46 (free base)
- References & Citations: [1]Yongjun Hu, et al. Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1677-1687.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
- Clinical Information: Phase 1