Recombinant Mouse CXCL9 (MIG)

Recombinant Mouse CXCL9 (MIG)

• Description: CXCL9 (MIG) is a T-cell chemoattractant. Induced by IFN-gamma (IFN-γ), the ELR-negative chemokine CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3. Mouse CXCL9 Recombinant Protein is purified CXCL9 (MIG) produced in yeast.
• Synonyms: Mouse ; CXCL9
• Label: ICT
• Type: Recombinant Protein
• Source: Yeast
• Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT (105)
• Assay Protocol: The Rat CCL4/MIP-1 beta protein can be used in cell culture, as an CCL4/MIP-1 beta ELISA Standard, and as a Western Blot Control., ,
• Form: Lyophilized
• Shipping Conditions: Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping
• Storage Temperature: -20°C
• Notes: 20% discount
• Calculated Molecular Weight: 12.2 kDa
• Target Description: Chemokine (C-X-C motif) ligand 9 (CXCL9), also commonly known as monokine induced by interferon-gamma (MIG), is a small cytokine belonging to the CXC chemokine family and is closely related to two other ELR-negative CXC chemokines: CXCL10 and CXCL11., , There have been 17 different C-X-C chemokines described in mammals that are subdivided into two categories: those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes., , CXCL9 (MIG) is a T-cell chemoattractant. Induced by IFN-gamma (IFN-γ), the ELR-negative chemokine CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3.