KBTBD8 Polyclonal Antibody
CAT:
866-RD89114A-03
Size:
200 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KBTBD8 Polyclonal Antibody
- Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
- Synonyms: TA-KRP,TAKRP,KBTBD8
- Gene ID: 84541
- Swiss Prot: Q8NFY9
- Host: Rabbit
- Reactivity: Mouse,Rat
- Immunogen: Recombinant fusion protein of human KBTBD8
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB
- Purification: Affinity purification
- Concentration: 1mg/mL
- Dilution: WB 1:500-1:2000
- Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
- Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- Observed Molecular Weight: 45kDa