PACRG Polyclonal Antibody

PACRG Polyclonal Antibody

• Background: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: PACRG,GLUP,HAK005771,PARK2CRG
• Gene ID: 135138
• Swiss Prot: Q96M98
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthetic peptide of human PACRG
• Clonality: Polyclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB
• Purification: Affinity purification
• Concentration: 1mg/mL
• Dilution: WB 1:500-1:2000
• Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
• Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 29kDa/60kDa
• Observed Molecular Weight: 61kDa