CD276/B7-H3 Polyclonal Antibody

CD276/B7-H3 Polyclonal Antibody

• Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2, CD276 antigen
• Gene ID: 80381
• Swiss Prot: Q5ZPR3
• Host: Rabbit
• Reactivity: Human
• Immunogen: A synthetic peptide of human CD276/B7-H3
• Clonality: Polyclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB
• Purification: Affinity purification
• Concentration: 1mg/mL
• Dilution: WB 1:500-1:2000
• Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
• Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 9kDa/12kDa
• Observed Molecular Weight: Refer to figures