Recombinant STAT5b Monoclonal Antibody

Recombinant STAT5b Monoclonal Antibody

• Background: STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands,such as IL2,IL4,CSF1,and different growth hormones. It has been shown to be involved in diverse biological processes,such as TCR signaling,apoptosis,adult mammary gland development,and sexual dimorphism of liver gene expression.
• Synonyms: STAT5,STAT5B
• Gene ID: 6777
• Swiss Prot: P51692
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: Recombinant protein of human STAT5b
• Clonality: Monoclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB,IHC-P
• Purification: Affinity purification
• Concentration: 300 μg/mL
• Dilution: WB 1:1000-1:2000, IHC 1:50-1:100
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
• Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 18kDa
• Observed Molecular Weight: 18kDa