IDO1 Polyclonal Antibody
CAT:
866-RD90156A-01
Size:
60 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IDO1 Polyclonal Antibody
- Background: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
- Synonyms: IDO1,IDO,IDO-1,INDO,indoleamine 2
- Gene ID: 3620
- Swiss Prot: P14902
- Host: Rabbit
- Reactivity: Human,Rat
- Immunogen: Recombinant fusion protein of human IDO1
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB
- Purification: Affinity purification
- Concentration: 1mg/mL
- Dilution: WB 1:500-1:2000
- Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
- Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- Calculated Molecular Weight: 46kDa/83kDa/154-165kDa
- Observed Molecular Weight: 160KDa